| Bioactivity | Ac-VDVAD-CHO is a caspase-2/3 inhibitor (IC50: 46 and 15 nM)[1]. |
| Target | caspase-2/3 |
| Name | Ac-VDVAD-CHO |
| CAS | 194022-51-0 |
| Sequence | Ac-Val-Asp-Val-Ala-Asp-CHO |
| Shortening | Ac-VDVAD-CHO |
| Formula | C23H37N5O10 |
| Molar Mass | 543.57 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Maillard MC, et al. Exploiting differences in caspase-2 and -3 S₂ subsites for selectivity: structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors. Bioorg Med Chem. 2011 Oct 1;19(19):5833-51. |