| Bioactivity | Ac-Trp-Glu-His-Asp-Aldehyde is a potent and selective caspase-1 inhibitor with a Ki value of 56 pM[1][2]. |
| Name | Ac-Trp-Glu-His-Asp-Aldehyde |
| CAS | 189275-71-6 |
| Sequence | Ac-Trp-Glu-His-{Asp-Aldehyde} |
| Shortening | Ac-WEH-{Asp-Aldehyde} |
| Formula | C28H33N7O9 |
| Molar Mass | 611.60 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kindermann M, et al. Selective and sensitive monitoring of caspase-1 activity by a novel bioluminescent activity-based probe. Chem Biol. 2010 Sep 24;17(9):999-1007. [2]. Rano TA, et al. A combinatorial approach for determining protease specificities: application to interleukin-1beta converting enzyme (ICE). Chem Biol. 1997 Feb;4(2):149-55. |