Bioactivity | Ac-PPPHPHARIK-NH2 (compound S1) is a compound that inhibits the interaction between androgen receptor and Src. It can inhibit the binding of androgen or estrogen-induced receptor and Src in cancer cells, as well as the activation of related signaling pathways, and can also inhibit cell cycle progression and tumor growth. |
CAS | 957791-38-7 |
Sequence | Ac-Pro-Pro-Pro-His-Pro-His-Ala-Arg-Ile-Lys-NH2 |
Shortening | Ac-PPPHPHARIK-NH2 |
Formula | C55H87N19O11 |
Molar Mass | 1190.40 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Inhibition of the SH3 domain-mediated binding of Src to the androgen receptor and its effect on tumor growth |