| Bioactivity | Ac-LETD-CHOis a caspases 8 inhibitor. Ac-LETD-CHO has specific inhibition to casp-8 withan IC50 value of 6.71 nM. Ac-LETD-CHOcan be used for the research of anticancer[1]. |
| Target | IC50: 6.71 nM (casp-8) |
| Name | Ac-LETD-CHO |
| Sequence | Ac-Leu-Glu-Thr-Asp-CHO |
| Shortening | Ac-LETD-CHO |
| Formula | C21H34N4O10 |
| Molar Mass | 502.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hu J, et al. MALDI-MS Patterning of Caspase Activities and Its Application in the Assessment of Drug Resistance. Angew Chem Int Ed Engl. 2016 Jun 1;55(23):6667-70. |