| Bioactivity | Ac-Gly-Ala-Lys(Ac)-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Gly-Ala-Lys(Ac)-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1]. |
| Name | Ac-Gly-Ala-Lys(Ac)-AMC |
| CAS | 577969-56-3 |
| Sequence | Ac-Gly-Ala-{Lys(Ac)}-{AMC} |
| Shortening | Ac-GA-{Lys(Ac)}-{AMC} |
| Formula | C25H33N5O7 |
| Molar Mass | 515.56 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ptacek J, et, al. Selectivity of Hydroxamate- and Difluoromethyloxadiazole-Based Inhibitors of Histone Deacetylase 6 In Vitro and in Cells. Int J Mol Sci. 2023 Mar 1;24(5):4720. |
Ac-Gly-Ala-Lys(Ac)-AMC
CAS: 577969-56-3 F: C25H33N5O7 W: 515.56
Ac-Gly-Ala-Lys(Ac)-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Gly-Ala-Lys(Ac)-AMC und
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