| Bioactivity | Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is a Caspase-3/7 inhibitor (IC50: 9.89, 245 nM respectively; Kiapp: 0.68, 55.7 nM respectively). Ac-DNLD-CHO can be used for research of caspase-mediated apoptosis diseases, such as neurodegenerative disorders and viral infection diseases[1]. |
| Target | Caspase-3/7 |
| Name | Ac-DNLD-CHO |
| CAS | 775289-20-8 |
| Sequence | Ac-Asp-Asn-Leu-Asp-CHO |
| Shortening | Ac-DNLD-CHO |
| Formula | C20H31N5O10 |
| Molar Mass | 501.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yoshimori A, et al. Structural and functional definition of the specificity of a novel caspase-3 inhibitor, Ac-DNLD-CHO. BMC Pharmacol. 2007 Jun 27;7:8. |
Ac-DNLD-CHO
CAS: 775289-20-8 F: C20H31N5O10 W: 501.49
Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is a Caspase-3/7 inhibitor (IC50: 9.89, 245 nM respectively; Kiapp: 0.68, 55.7 nM r
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