| Bioactivity | Ac-DMQD-pNA is a peptide substrate. Both of the recombinant CgCaspase-1 (rCgCaspase-1) and the C-terminus of CgCaspase-1 (rCgCaspase-1-C) exhibits similar caspase activity towards proteolytic substrate Ac-DMQD-pNA and Ac-DEVD-pNA (HY-P1006)[1][2]. |
| Name | Ac-DMQD-pNA |
| CAS | 907589-02-0 |
| Sequence | Ac-Asp-Met-Gln-Asp-{pNA} |
| Shortening | Ac-DMQD-{pNA} |
| Formula | C26H35N7O12S |
| Molar Mass | 669.66 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Fang B, et al. Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition. J Mol Biol. 2006 Jul 14;360(3):654-66. [2]. Lu G, et al. The self-activation and LPS binding activity of executioner caspase-1 in oyster Crassostrea gigas. Dev Comp Immunol. 2017 Dec;77:330-339. |
Ac-DMQD-pNA
CAS: 907589-02-0 F: C26H35N7O12S W: 669.66
Ac-DMQD-pNA is a peptide substrate. Both of the recombinant CgCaspase-1 (rCgCaspase-1) and the C-terminus of CgCaspase-1
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