Bioactivity | Ac-DMQD-AMC is an inhibitor of caspase-3. Ac-DMQD-AMC is an aromatic amine using aminium-based coupling reagent HATU in the presence of 2,4,6-trimethylpyridine (TMP)[1]. |
Name | Ac-DMQD-AMC |
CAS | 355137-38-1 |
Sequence | Ac-Asp-Met-Gln-Asp-{AMC} |
Shortening | Ac-DMQD-{AMC} |
Formula | C30H38N6O12S |
Molar Mass | 706.72 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Przemysław Reszka, et al. Control of aspartate epimerization during the coupling of caspase specific tetrapeptides with aromatic amines by using N-[[(dimethylamino)-1H-1,2,3-triazolo[4,5-b]-pyridin-1-yl]methylene]-N-methylmethanaminium hexafluorophosphate N-oxide (HATU) as a coupling reagent. Tetrahedron: Asymmetry. 2008, 19, 1. |