| Bioactivity | Ac-Arg-Gly-Lys-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Arg-Gly-Lys-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1]. |
| Name | Ac-Arg-Gly-Lys-AMC |
| CAS | 660846-99-1 |
| Sequence | Ac-Arg-Gly-Lys-{AMC} |
| Shortening | Ac-RGK-{AMC} |
| Formula | C26H38N8O6 |
| Molar Mass | 558.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Noonepalle S, et, al. Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models. J Med Chem. 2020 Sep 24;63(18):10246-10262. |
Ac-Arg-Gly-Lys-AMC
CAS: 660846-99-1 F: C26H38N8O6 W: 558.63
Ac-Arg-Gly-Lys-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Arg-Gly-Lys-AMC undergoes h
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