| Bioactivity | Abacavir sulfate (Abacavir Hemisulfate) is a competitive, orally active nucleoside reverse transcriptase inhibitor. Abacavir sulfate can inhibits the replication of HIV. Abacavir sulfate shows anticancer activity in prostate cancer cell lines. Abacavir sulfate can trespass the blood-brain-barrier and suppresses telomerase activity[1][2][3]. |
| Invitro | Abacavir (15 and 150 μM, 0-120 h) sulfate inhibits cell growth, affects cell cycle progression, induces senescence and modulates LINE-1 mRNA expression in prostate cancer cell lines[1]. Abacavir (15 and 150 μM, 18 h) sulfate significantly reduces cell migration and inhibits cell invasion[1].Abacavir sulfate induces fat apoptosis[4]. Cell Proliferation Assay[1] Cell Line: |
| Name | Abacavir sulfate |
| CAS | 188062-50-2 |
| Formula | C14H18N6O.1/2H2O4S |
| Molar Mass | 335.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
Abacavir sulfate
CAS: 188062-50-2 F: C14H18N6O.1/2H2O4S W: 335.38
Abacavir sulfate (Abacavir Hemisulfate) is a competitive, orally active nucleoside reverse transcriptase inhibitor. Abac
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