| Bioactivity | Abacavir hydroxyacetate is an orally active inhibitor of IL-20 and PRINS. Abacavir hydroxyacetate reduces proliferation rate of skin in psoriasis as an immune modulator. Abacavir hydroxyacetate can be used for the research of inflammatory skin problems[1][2]. | |||||||||
| In Vivo | Abacavir hydroxyacetate (10-20 mg/kg; p.o. once) effectively controls psoriasis of mice[2]. Animal Model: | |||||||||
| Name | Abacavir hydroxyacetate | |||||||||
| CAS | 1446418-48-9 | |||||||||
| Formula | C16H20N6O3 | |||||||||
| Molar Mass | 344.37 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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| Reference | [1]. Guda A, et al. Investigational drugs in phase II clinical trials for moderate to severe plaque psoriasis - potential new treatments on the horizon. Expert Opin Investig Drugs. 2018 Nov;27(11):931-939. [2]. Menon, et al. CARBOCYCLIC NUCLEOSIDES AND THEIR PHARMACEUTICAL USE AND COMPOSITIONS. WO/2013/103601/Al. |
Abacavir hydroxyacetate
CAS: 1446418-48-9 F: C16H20N6O3 W: 344.37
Abacavir hydroxyacetate is an orally active inhibitor of IL-20 and PRINS. Abacavir hydroxyacetate reduces proliferation
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