| Bioactivity | AZSMO-23 is a potent hERG K+ channel activator. AZSMO-23 activats WT hERG pre-pulse and tail current with EC50 values of 28.6, 11.2 µM, respectively. AZSMO-23 has the potential for the research of long QT syndrome[1]. |
| Invitro | AZSMO-23 阻断 hKv4.3-hKChIP2.2、hCav3.2 和 hKv1.5 通道并激活 hCav1.2/β2/α2δ 通道[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> AZSMO-23 相关抗体: |
| CAS | 496793-75-0 |
| Formula | C19H13ClN4O |
| Molar Mass | 348.79 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mannikko R, et al. Pharmacological and electrophysiological characterization of AZSMO-23, an activator of the hERG K(+) channel. Br J Pharmacol. 2015 Jun;172(12):3112-25. |
AZSMO-23
CAS: 496793-75-0 F: C19H13ClN4O W: 348.79
AZSMO-23 is a potent hERG K+ channel activator. AZSMO-23 activats WT hERG pre-pulse and tail current with EC50 values of
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