| Bioactivity | AZD8542 is an antagonist of Smoothened (SMO), playing an important role in oncology. AZD8542 is a? Hedgehog (Hh) pathway antagonist on tumor progression with an emphasis on the role of the stroma compartment[1][2]. |
| Name | AZD8542 |
| CAS | 1126366-36-6 |
| Formula | C25H24N4O2 |
| Molar Mass | 412.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Rosa F. Hwang, INHIBITION OF THE HEDGEHOG PATHWAY TARGETS THE TUMOR-ASSOCIATED STROMA IN PANCREATIC CANCER. Mol Cancer Res. 2012 Sep; 10(9): 1147–1157. [2]. Dakin Leslie, et al. Preparation of amide compounds containing heterocycle moiety as hedgehog pathway inhibitors. World Intellectual Property Organization, WO2009027746 A1 |