Bioactivity | AZD8309 is an orally active antagonist of CXCR2. AZD8309 has the ability to regulate the transmigration of neutrophils. AZD8309 can be used in the study of inflammatory diseases[1]. |
In Vivo | AZD8309 (50 mg/kg; 口服给药; 每天 2 次) 降低小鼠实验性胰腺炎中性粒细胞迁移和胰腺蛋白酶激活[1]。 Animal Model: |
Name | AZD8309 |
CAS | 333742-48-6 |
Formula | C15H14F2N4O2S2 |
Molar Mass | 384.42 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Malla SR, et al. Effect of oral administration of AZD8309, a CXCR2 antagonist, on the severity of experimental pancreatitis. Pancreatology. 2016 Sep-Oct;16(5):761-9. |