| Bioactivity | AZD5597 is an inhibitor of CDK with an IC50 of 2 nM. AZD5597 has potent anti-proliferative effects against a range of cancer cell lines[1]. |
| Target | IC50: 2 nM (CDK2), 2 nM (CDK1), 39 nM (LoVo) |
| Name | AZD5597 |
| CAS | 924641-59-8 |
| Formula | C23H28FN7O |
| Molar Mass | 437.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jones CD, et al.The discovery of AZD5597, a potent imidazole pyrimidine amide CDK inhibitor suitable for intravenous dosing. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6369-73. |