Bioactivity | AZD4694 Precursor (AZ13040214) is the precursor of [18F] AZD4694 for the synthesis of [18F] AZD4694, an amyloid-β imaging ligand with high affinity for amyloid-β plaques[1]. | ||||||||||||
Invitro | AZD4694 Precursor is an amyloid-β imaging ligand with high affinity for amyloid-β plaques. AZD4694 Precursor is a high affinity (Kd= 2.3 nM) radioligand for imaging amyloid-β plaques that displays lower white matter binding compared to other fluorinated amyloid-PET tracers, enabling easier visual reads[1]. | ||||||||||||
Name | AZD4694 Precursor | ||||||||||||
CAS | 1211333-20-8 | ||||||||||||
Formula | C22H25N3O7 | ||||||||||||
Molar Mass | 443.45 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Therriault J, et al. Determining Amyloid-β Positivity Using 18F-AZD4694 PET Imaging. J Nucl Med. 2021;62(2):247-252. |