| Bioactivity | AZD-7648 is a potent, orally active, selective DNA-PK inhibitor with an IC50 of 0.6 nM. AZD-7648 induces apoptosis and shows antitumor activity[1]. | ||||||||||||
| Invitro | AZD7648 (0-30 μM) is a potent radiosensitizer[1].AZD7648 (3 μM) increases sensitivity to doxorubicin[1].AZD7648 (0.6 μM) enhances the activity of PARP inhibitor olaparib[1]. Western Blot Analysis[1] Cell Line: | ||||||||||||
| Name | AZD-7648 | ||||||||||||
| CAS | 2230820-11-6 | ||||||||||||
| Formula | C18H20N8O2 | ||||||||||||
| Molar Mass | 380.40 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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AZD-7648
CAS: 2230820-11-6 F: C18H20N8O2 W: 380.40
AZD-7648 is a potent, orally active, selective DNA-PK inhibitor with an IC50 of 0.6 nM. AZD-7648 induces apoptosis and s
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