| Bioactivity | AZD 4407 is a potent 5-lipoxygenase inhibitor. |
| Invitro | In view of the powerful spasmogenic actions of leukotrienes in vascular and bronchial tissue, drugs which block their biosynthesis by inhibiting 5-lipoxygenase may have therapeutic potential in a variety of inflammatory conditions including inflammatory arthropothies, asthma, psoriasis, and inflammatory bowel disease. One such compound is AZD 4407 (ZD4407)[1]. |
| Name | AZD 4407 |
| CAS | 166882-70-8 |
| Formula | C19H21NO3S2 |
| Molar Mass | 375.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jonathan Hutton, et al. Use of a Titanium Thienyl Anion and a Simple Procedure for Introducing a Thiol Group into Thiophene in the Development of a Manufacturing Route to the 5-Lipoxygenase Inhibitor ZD4407. Org Process Res Dev. 1997 Jan 15;1(1): 61–67. |