AZ'3137_product_DataBase

Bioactivity	AZ'3137 (Compound 22) is an orally active androgen receptor (AR) degrader. AZ'3137 can inhibit cell proliferation of LNCaP, with a GI50 value of 74 nM. AZ'3137 can inhibit AR signaling and tumor growth in prostate cancer mice[1].
Invitro	AZ'3137 (Compound 22) 可以抑制 AR 信号传导和前列腺癌细胞系 LNCaP 的细胞增殖[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> AZ'3137 相关抗体: Cell Proliferation Assay[1]. Cell Line:
In Vivo	AZ'3137 (Compound 22) 在前列腺癌小鼠中抑制肿瘤生长[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
CAS	2960179-55-7
Formula	C43H47F4N7O4
Molar Mass	801.87
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Bagal SK, et al. Discovery of a Series of Orally Bioavailable Androgen Receptor Degraders for the Treatment of Prostate Cancer. J Med Chem. 2024 Jul 25;67(14):11732-11750.

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