| Bioactivity | AZ14240475 is a potent, selective, and brain-penetrant inhibitor of EGFR Ex20Ins mutants, with the pIC50 of 7.6. AZ14240475 plays an important role in cancer research[1]. |
| Formula | C23H15ClF2N6O2 |
| Molar Mass | 480.85 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. William McCoull, et al. Highly Optimized CNS Penetrant Inhibitors of EGFR Exon20 Insertion Mutations. J Med Chem. 2025 Jan 27. |