Bioactivity | AVE1231 (A293) is a dual-pore potassium channel TASK-1 inhibitor with antiarrhythmic activity[1]. |
CAS | 767334-89-4 |
Formula | C20H27N3O4S |
Molar Mass | 405.51 |
Appearance | 固体 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
Reference | [1]. Wiedmann F, et al. Identification of the A293 (AVE1231) binding site in the cardiac two-pore-domain potassium channel TASK-1: a common low affinity antiarrhythmic drug binding site[J]. Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2019, 52(5). |