Bioactivity | AU-224 is a benzamide derivative used as a promising gastrointestinal prokinetic agent without significant side effects. |
Invitro | AU-224 is a benzamide derivative used as a promising gastrointestinal prokinetic agent without significant side effects. |
In Vivo | AU-224 has excellent effect of promoting digestive motion while showing little side effect and can be orally administered[1]. AU-224 shows only weak gastrointestinal prokinetic activity after oral administration due to its low lipophilicity[2]. |
Name | AU-224 |
CAS | 287399-47-7 |
Formula | C19H28ClN3O4 |
Molar Mass | 397.90 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. WO/2000/046201A1 [2]. Sakaguchi J, et al. An improved synthesis of butyl 4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]-1-piperidineacetate (AU-224). Chem Pharm Bull (Tokyo). 2001 Jun;49(6):788-90. |