| Bioactivity | ATX inhibitor 16 is a potent ATX inhibitor with an IC50 of 0.0021 µM. ATX inhibitor 16 shows excellent anti-proliferative activities in breast cancer cells[1]. |
| Target | IC50: 0.0021 µM (ATX) |
| Invitro | ATX inhibitor 16 (compound 9j) (0-15 µM; 72 h) shows excellent anti-proliferative activities in breast cancer cells[1]. Cell Cytotoxicity Assay[1] Cell Line: |
| Name | ATX inhibitor 16 |
| CAS | 2484811-36-9 |
| Formula | C28H27F3N6OS2 |
| Molar Mass | 584.68 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lei H,et al. Structure guided design of potent indole-based ATX inhibitors bearing hydrazone moiety with tumor suppression effects. Eur J Med Chem. 2020 Sep 1;201:112456. |