| Bioactivity | ATV2301 is an orally active anti-influenza agent (EC50, H1N1 = 1.88 nM, H3N2 = 4.77 nM). ATV2301’s anti-influenza activity is due to its effects on polymerase acid protein (PA), nuclear protein (NP), and RNA-dependent RNA polymerase (RdRp)[1]. |
| CAS | 3049172-60-0 |
| Formula | C21H17F2N3O4S |
| Molar Mass | 445.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yongzhi Chen, et al. Discovery of Novel Thiophene-Based Baloxavir Derivatives as Potent Cap-Dependent Endonuclease Inhibitors for Influenza Treatment. J Med Chem. 2024 Dec 26;67(24):22039-22054. |
ATV2301
CAS: 3049172-60-0 F: C21H17F2N3O4S W: 445.44
ATV2301 is an orally active anti-influenza agent (EC50, H1N1 = 1.88 nM, H3N2 = 4.77 nM). ATV2301’s anti-influenza activ
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