| Bioactivity | ATV03 is an anti-influenza virus agent with excellent anti-influenza A and B virus activity. ATV03 inhibits anti-influenza A (H3N2) and anti-influenza B with EC50 values of 0.78 nM and 2.02 nM, respectively. ATV03 exerts anti-influenza activity by inhibiting polymerase acidic protein (PA) and RNA-dependent RNA polymerase (RdRp), as well as disrupting nuclear protein[1]. |
| Formula | C24H20FN3O5 |
| Molar Mass | 449.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yongzhi Chen, et al. Synthesis and anti-influenza virus activity of substituted dibenzoxepine-based baloxavir derivatives. Eur J Med Chem. 2024 Sep 28:280:116922. |