Bioactivity | ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation[1][2]. | ||||||||||||
Invitro | ATP (5 mM; 1 hour) co-treatment with LPS (1 μg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs[3].ATP (2 mM; 0.5-24 hours) induces secretion of IL-1β, KC and MIP-2 from BMDMs in a caspase-1 activation-dependent manner[4].ATP promotes neutrophil chemotaxis in vitro[4]. | ||||||||||||
Name | ATP | ||||||||||||
CAS | 56-65-5 | ||||||||||||
Formula | C10H16N5O13P3 | ||||||||||||
Molar Mass | 507.18 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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