| Bioactivity | ATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex, inhibits mitochondrial permeability transition pore (mPTP) opening, does not affect ATP levels[1]. | ||||||
| Target | F1/FO-ATP synthase | ||||||
| Invitro | ATP synthase inhibitor 1 (Compound 10) is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex[1]. | ||||||
| Name | ATP synthase inhibitor 1 | ||||||
| CAS | 1023043-30-2 | ||||||
| Formula | C17H18ClN3O3S2 | ||||||
| Molar Mass | 411.93 | ||||||
| Appearance | Solid | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage |
*该产品在溶液状态不稳定,建议您现用现配,即刻使用。 |
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| Reference | [1]. Morciano G, et al. Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction. J Med Chem. 2018 Aug 23;61(16):7131-7 |