Bioactivity | ATAC21, a linker-immune-stimulatory compound that can be formed by conjugating a noncleavable maleimide-PEG4 linker containing a succinimide group with an immune- stimulatory compound. ATAC21 can be combined with SBT-040 (anti-CD40 antibody) to form a conjugate[1]. |
Invitro | 一种重组双特异性抗体,包括:a)靶抗原结合结构域,其中所述靶抗原结合结构域特异性结合肿瘤相关抗原; b)效应抗原结合结构域,其中效应抗原结合结构域特异性结合抗原呈递细胞上的抗原,并且其中抗原是抗原呈递细胞上的分子; c) 包含 Fc 的结构域; d)通过连接子连接到重组双特异性抗体上的免疫刺激化合物; 其中与重组双特异性抗体结合抗原呈递细胞上的抗原时相比,当重组双特异性抗体结合肿瘤相关抗原和抗原呈递细胞上的抗原时,重组双特异性抗体诱导更大的免疫细胞活化,但是不是肿瘤相关抗原[1]。 |
Name | ATAC21 |
CAS | 2101204-23-1 |
Formula | C38H50N12O21P2 |
Molar Mass | 1072.82 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |