| Bioactivity | AT1R antagonist 2 (compound 6) is a potent AT1R selective ligand. AT1R antagonist 2 exhibits a fair AT1R affinity, with a Ki of 26 nM[1]. |
| Target | Ki: 26 nM (AT1R), 480 nM (AT2R) |
| Name | AT1R antagonist 2 |
| Formula | C29H37N5O4S2 |
| Molar Mass | 583.77 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bolteau R, et al. Quinazoline and phthalazine derivatives as novel melatonin receptor ligands analogues of agomelatine. Eur J Med Chem. 2020 Mar 1;189:112078. |