| Bioactivity | AT-9010, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 can inhibit SARS-CoV-2 replication[1]. |
| Target | NiRAN |
| Invitro | Substantial levels of the active triphosphate metabolite AT-9010 are formed in normal human bronchial and nasal epithelial cells incubated with 10 µM AT-511 (698 µM and 236 µM, respectively), with a half-life of at least 38 hours[1]. |
| Name | AT-9010 |
| CAS | 1261253-79-5 |
| Formula | C11H17FN5O13P3 |
| Molar Mass | 539.20 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Atea Pharmaceuticals Announces Publication of Preclinical Data Highlighting Potent Activity of AT-527 Against SARS-CoV-2. BOSTON, Feb. 08, 2021. Atea Pharmaceuticals, Inc. |
AT-9010
CAS: 1261253-79-5 F: C11H17FN5O13P3 W: 539.20
AT-9010, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral repl
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