| Bioactivity | AT-121 is a bifunctional nociception and mu opioid receptor agonist, with Kis of 3.67 and 16.49 nM, respectively. AT-121 is a safe, non-addictive analgesic, and shows antinociceptive and antiallodynic effects[1]. |
| In Vivo | AT-121 (0.003-0.03 mg/kg; s.c.) produces potent antinociceptive effect[1]. Animal Model: |
| Name | AT-121 |
| CAS | 2099681-31-7 |
| Formula | C24H38N4O3S |
| Molar Mass | 462.65 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ding H, Kiguchi N, Yasuda D, et al. A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates. Sci Transl Med. 2018;10(456):eaar3483. doi:10.1126/scitranslmed.aar3483 |