PeptideDB

ASR-488

CAS: 2690312-65-1 F: C33H40O7S W: 580.73

ASR-488 activates the mRNA-binding protein CPEB1, induces apoptosis and inhibits bladder cancer growth.
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Bioactivity ASR-488 activates the mRNA-binding protein CPEB1, induces apoptosis and inhibits bladder cancer growth[1].
Invitro ASR-488 (0.2-12.5 µM,24-72 h) 可有效诱导细胞凋亡信号并显着抑制 TCCSUP 和 HT1376 细胞的生长[1]。 Cell Proliferation Assay[1] Cell Line:
Name ASR-488
CAS 2690312-65-1
Formula C33H40O7S
Molar Mass 580.73
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Ashish Tyagi, et al. ASR488, a novel small molecule, activates an mRNA binding protein, CPEB1, and inhibits the growth of bladder cancer. Oncol Lett. 2020 Jul;20(1):850-860.