Bioactivity | ASR-488 activates the mRNA-binding protein CPEB1, induces apoptosis and inhibits bladder cancer growth[1]. | |||||||||
Invitro | ASR-488 (0.2-12.5 µM,24-72 h) 可有效诱导细胞凋亡信号并显着抑制 TCCSUP 和 HT1376 细胞的生长[1]。 Cell Proliferation Assay[1] Cell Line: | |||||||||
Name | ASR-488 | |||||||||
CAS | 2690312-65-1 | |||||||||
Formula | C33H40O7S | |||||||||
Molar Mass | 580.73 | |||||||||
Appearance | Solid | |||||||||
Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
Storage |
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Reference | [1]. Ashish Tyagi, et al. ASR488, a novel small molecule, activates an mRNA binding protein, CPEB1, and inhibits the growth of bladder cancer. Oncol Lett. 2020 Jul;20(1):850-860. |