PeptideDB

ASP8302

CAS: 1839583-42-4 F: C26H32ClN7O3S2 W: 590.16

ASP8302 is a positive allosteric modulator of muscarinic M3 Receptor. ASP8302 improves voiding efficiency and reduced re
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Bioactivity ASP8302 is a positive allosteric modulator of muscarinic M3 Receptor. ASP8302 improves voiding efficiency and reduced residual urine volume in two voiding dysfunction models. ASP8302 can be used for research of underactive bladder[1][2].
CAS 1839583-42-4
Formula C26H32ClN7O3S2
Molar Mass 590.16
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Okimoto R, et al. Potentiation of Muscarinic M3 Receptor Activation through a New Allosteric Site with a Novel Positive Allosteric Modulator ASP8302. J Pharmacol Exp Ther. 2021 Oct;379(1):64-73. [2]. Okimoto R, et al. Muscarinic M3 positive allosteric modulator ASP8302 enhances bladder contraction and improves voiding dysfunction in rats. Low Urin Tract Symptoms. 2022 Jul;14(4):289-300.