Bioactivity | ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. ASK1-IN-2 can be used for the research of ulcerative colitis[1]. | ||||||||||||
Invitro | ASK1-IN-2 (compound 19) (10 mM; 1 h) inhibits the luciferase reporter activity in AP1-HEK293 cells, with inhibition rate of 95.59%[1]. | ||||||||||||
Name | ASK1-IN-2 | ||||||||||||
CAS | 2541792-70-3 | ||||||||||||
Formula | C19H17FN6O | ||||||||||||
Molar Mass | 364.38 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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