| Bioactivity | ARUK2001607 is a selective phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor with a Kd of 7.1 nM. ARUK2001607 shows high selectivity over other >150 kinases[1]. |
| Target | Kd: 7.1 nM (PI5P4Kγ) |
| In Vivo | In Vivo Mouse Pharmacokinetics Parameters for Selected ARUK2001607 (15) (5 mg/kg; ip Administration)[1] |
| Name | ARUK2001607 |
| Formula | C14H13N3O2S2 |
| Molar Mass | 319.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Timothy P C Rooney, et al. The Identification of Potent, Selective, and Brain Penetrant PI5P4Kγ Inhibitors as In Vivo-Ready Tool Molecules. J Med Chem. 2022 Dec 14. |