| Bioactivity | ARN726 is a potent NAAA (N-acylethanolamine acid amidase) inhibitor with an IC50 of 0.073 µM. ARN726 decreases alcohol self-administration in a dose-dependent manner[1][2]. |
| Target | NAAA |
| Name | ARN726 |
| CAS | 1628343-77-0 |
| Formula | C14H24N2O3 |
| Molar Mass | 268.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Fotio Y, et al. N-acylethanolamine acid amidase (NAAA) inhibition decreases the motivation for alcohol in Marchigian Sardinian alcohol-preferring rats. Psychopharmacology (Berl). 2021 Jan;238(1):249-258. [2]. Petracca R, et al. Novel activity-based probes for N-acylethanolamine acid amidase. Chem Commun (Camb). 2017 Aug 22;53(86):11810-11813. |