| Bioactivity | AR antagonist 6 (compound 6i) is a diphenyl ether androgen receptor (AR) antagonist that binds AR at a concentration of 120 nM. AR antagonist 6 exhibits low toxicity and in vitro activity against the golden Syrian hamster ear model.[19][1]. |
| Invitro | AR antagonist 6 在细胞中对 AR 的抑制浓度为 47 nM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> AR antagonist 6 相关抗体: |
| CAS | 876760-08-6 |
| Formula | C16H12F3NO2 |
| Molar Mass | 307.27 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mitchell LH, et al. Diphenyl ethers as androgen receptor antagonists for the topical suppression of sebum production. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2176-8. |
AR antagonist 6
CAS: 876760-08-6 F: C16H12F3NO2 W: 307.27
AR antagonist 6 (compound 6i) is a diphenyl ether androgen receptor (AR) antagonist that binds AR at a concentration of
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