Bioactivity | AR-M1896 is a GalR2 selective agonist with a binding IC50 of 1.76 nM for rat GalR2. AR-M1896 can be used for the research of acute myocardial infarction and neuropathic pain[1][2]. |
Target | IC50: 1.76 nM (rat GalR2), 879 nM (hGalR1) |
Name | AR-M1896 |
CAS | 367518-31-8 |
Sequence | Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-NH2 |
Shortening | WTLNSAGYLL-NH2 |
Formula | C54H81N13O14 |
Molar Mass | 1136.30 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Liu HX, et al. Receptor subtype-specific pronociceptive and analgesic actions of galanin in the spinal cord: selective actions via GalR1 and GalR2 receptors. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9960-4. [2]. Serebryakova L, et al. Galanin and its N-terminal fragments reduce acute myocardial infarction in rats. Peptides. 2019 Jan;111:127-131. |