PeptideDB

AR-M1896

CAS: 367518-31-8 F: C54H81N13O14 W: 1136.30

AR-M1896 is a GalR2 selective agonist with a binding IC50 of 1.76 nM for rat GalR2. AR-M1896 can be used for the researc
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Bioactivity AR-M1896 is a GalR2 selective agonist with a binding IC50 of 1.76 nM for rat GalR2. AR-M1896 can be used for the research of acute myocardial infarction and neuropathic pain[1][2].
Target IC50: 1.76 nM (rat GalR2), 879 nM (hGalR1)
Name AR-M1896
CAS 367518-31-8
Sequence Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-NH2
Shortening WTLNSAGYLL-NH2
Formula C54H81N13O14
Molar Mass 1136.30
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Liu HX, et al. Receptor subtype-specific pronociceptive and analgesic actions of galanin in the spinal cord: selective actions via GalR1 and GalR2 receptors. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9960-4. [2]. Serebryakova L, et al. Galanin and its N-terminal fragments reduce acute myocardial infarction in rats. Peptides. 2019 Jan;111:127-131.