| Bioactivity | APPA is an aldose reductase inhibitor. APPA can effectively prevent apoptosis and the symptoms of Streptozotocin (HY-13753)-induced diabetes by inhibiting the polyol pathway in rats. APPA has the potential for diabetic nephropathy (DN) research[1]. |
| Name | APPA |
| CAS | 100750-39-8 |
| Formula | C14H13NO3 |
| Molar Mass | 243.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhi-Ming Xiu, et al. 1-Acetyl-5-phenyl-1H-pyrrol-3-ylacetate: An aldose reductase inhibitor for the treatment of diabetic nephropathy. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4482-4487. |