| Bioactivity | APOL1-IN-2 (Compound 467) is the inhibitor for Apolipoprotein 1 (APOL1). APOL1-IN-2 reduces the APOL1 G2/G1 induced cell death in HEK293 with EC50 of 4.74 nM and 14.3 nM. APOL1-IN-2 reduces the APOL1 G2/G1/G0 induced death of trypanosomes with EC50 of 2.24, 6.03 and 3.72 nM, respectively[1]. |
| CAS | 2956781-84-1 |
| Formula | C28H30ClF3N4O5 |
| Molar Mass | 595.01 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lee PST, et al., APOL1 inhibitors and methods of use. US11976067B2 |
APOL1-IN-2
CAS: 2956781-84-1 F: C28H30ClF3N4O5 W: 595.01
APOL1-IN-2 (Compound 467) is the inhibitor for Apolipoprotein 1 (APOL1). APOL1-IN-2 reduces the APOL1 G2/G1 induced cell
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