Bioactivity | APL-1091 (Mal-Exo-EEVC-MMAE) is part of a Drug-linker conjugate for ADC. APL-1091 contains a Mal-Exo-EEVC (HY-169353) linker and MMAE (HY-15162) (Microtubule inhibitor). APL-1091 can be used for ADC synthesis[1]. |
CAS | 2921735-87-5 |
Formula | C80H122N14O22 |
Molar Mass | 1631.91 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Watanabe T, et al. Exo-Cleavable Linkers: Enhanced Stability and Therapeutic Efficacy in Antibody-Drug Conjugates. J Med Chem. 2024 Oct 24;67(20):18124-18138. |