| Bioactivity | APC 366 (TFA) is an irreversible mast cell tryptase inhibitor. APC 366 (TFA) can be used for the research of allergic diseases[1]. |
| Target | mast cell tryptase |
| In Vivo | APC 366 (TFA) (5 mg/kg/0.1 ml; s.c.) reduces the eosinophil recruitment induced by PAR-2 activating peptide[1]. Animal Model: |
| Name | APC 366 TFA |
| CAS | 2421110-28-1 |
| Formula | C24H29F3N6O6 |
| Molar Mass | 554.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Matos NA, et al. Mast cell tryptase induces eosinophil recruitment in the pleural cavity of mice via proteinase-activated receptor 2. Inflammation. 2013;36(6):1260-1267. |
APC 366 TFA
CAS: 2421110-28-1 F: C24H29F3N6O6 W: 554.52
APC 366 (TFA) is an irreversible mast cell tryptase inhibitor. APC 366 (TFA) can be used for the research of allergic di
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