| Bioactivity | ANQ-11125 TFA is a potent and selective antagonist of motilin, with the pKd of 8.24. ANQ-11125 TFA blocks motilide-induced contractions in vitro in the rabbit[1][2]. |
| Target | pKd: 8.24 (motilin) |
| Name | ANQ-11125 TFA |
| Shortening | FVFIFTYGELQRLQ |
| Formula | C88H126F3N19O23 |
| Molar Mass | 1875.05 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Depoortere I, et, al. Antagonistic properties of [Phe3,Leu13]porcine motilin. Eur J Pharmacol. 1995 Nov 24; 286(3):241-7. [2]. Peeters TL, et, al. The motilin antagonist ANQ-11125 blocks motilide-induced contractions in vitro in the rabbit. Biochem Biophys Res Commun. 1994 Jan 28; 198(2): 411-6. |