| Bioactivity | AN5777 is a GSPT1 degrader. AN5777 significantly reduces GSPT1 through the ubiquitin-proteasome system. AN5777 induces G1 block and Apoptosis. AN5777 has antitumor activity [1]. |
| CAS | 491586-42-6 |
| Formula | C19H17N3O2 |
| Molar Mass | 319.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhang S, et al. Identification of novel GSPT1 degraders by virtual screening and bioassay. Eur J Med Chem. 2024 Jul 5;273:116524. |