| Bioactivity | AMT-NHS is an RNA-protein crosslinker. AMT-NHS is composed of a psoralen derivative and an N-hydroxysuccinimide ester group which react with RNA bases and primary amines of protein, respectively. AMT-NHS can penetrate into living yeast cells and crosslink Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces different crosslinking patterns and targets both single- and double-stranded regions of RNA. AMT-NHS can be used for capturing diverse RNA-protein interactions in cells[1]. |
| Name | AMT-NHS |
| Formula | C22H21NO7S |
| Molar Mass | 443.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Han Y, et al. Development of an RNA-protein crosslinker to capture protein interactions with diverse RNA structures in cells. RNA. 2022 Mar;28(3):390-399. |