| Bioactivity | AMPte-Glu-γ-Glu is a substrate for folylpoly-γ-glutamate synthetase (FPGS). AMPte-Glu-γ-Glu exhibits cytotoxicity against chinese hamster ovaries cells, with IC50s of 20, 350 and 3 nM, for Pro3, R2, and 43-10, respectively[1]. |
| CAS | 41600-13-9 |
| Formula | C25H29N9O8 |
| Molar Mass | 583.55 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Feng Y, et al., Prodrug forms of N-[(4-deoxy-4-amino-10-methyl)pteroyl]glutamate-gamma-[psiP(O)(OH)]-glutarate, a potent inhibitor of folylpoly-gamma-glutamate synthetase: synthesis and hydrolytic stability. J Med Chem. 2006 Jan 26;49(2):770-88. |
AMPte-Glu-γ-Glu
CAS: 41600-13-9 F: C25H29N9O8 W: 583.55
AMPte-Glu-γ-Glu is a substrate for folylpoly-γ-glutamate synthetase (FPGS). AMPte-Glu-γ-Glu exhibits cytotoxicity aga
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