| Bioactivity | AMC-04 is an unfolded protein response (UPR) activator, which activates UPR pathway through ROS and p38 MAPK signaling and induces apoptotic cell death. AMC-04 can be used for cancer research[1]. |
| Invitro | AMC-04 (10-40 μM, 24-48 h) 时间和剂量依赖性地诱导 MCF-7 细胞凋亡，上调内质网应激反应基因和 CHOP 依赖性 DR5，并抑制 H3K9 甲基转移酶活性[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> AMC-04 相关抗体: |
| CAS | 792928-94-0 |
| Formula | C26H28N2O3 |
| Molar Mass | 416.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kim SY, et al. Molecular mechanisms underlying the effects of the small molecule AMC-04 on apoptosis: Roles of the activating transcription factor 4-C/EBP homologous protein-death receptor 5 pathway. Chem Biol Interact. 2020 Dec 1;332:109277. |