| Bioactivity | AM8936 acts as a balanced and potent cannabinoid receptor type-1 (CB1) agonist in functional assays (EC50s of 8.6 and 1.4 nM for rCB1 and hCB1, respectively). AM8936 exhibits high affinity for rat CB1 (rCB1) with Ki of 0.55 nM. AM8936 is a potent and efficacious CB1 agonist in vivo. AM8936 can be used for the research of CNS and metabolic disorders, pain, glaucoma, etc[1]. |
| Name | AM8936 |
| Formula | C25H33NO3 |
| Molar Mass | 395.53 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ioannis P Papanastasiou, et al. Improved cyclobutyl nabilone analogs as potent CB1 receptor agonists. Eur J Med Chem. 2022 Feb 15;230:114027. |