| Bioactivity | ALR2-IN-2 is a potent inhibitor of aldose reductase (ALR2), with IC50s of 27 nM and 228 nM for rat ALR2 and ALR1, respectively. ALR2-IN-2 can be used for the research of diabetic complications[1]. |
| Target | IC50: 27 nM (rat ALR2), 228 nM (rat ALR1) |
| Invitro | ALR2-IN-2 (化合物 2d) 抑制大鼠晶状体 ALR2 和大鼠肾脏 ALR1，IC50 值分别为为 27 nM 和 228 nM[1]。 |
| Name | ALR2-IN-2 |
| Formula | C17H11FN2O2S2 |
| Molar Mass | 358.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kratky M, et, al. Novel rhodanine based inhibitors of aldose reductase of non-acidic nature with p-hydroxybenzylidene functional group. Eur J Med Chem. 2022 Nov 12;246:114922. |