Bioactivity | ALPK1-IN-1 (Compound A001) is a potent inhibitor of alpha-kinase 1 (ALPK1). ALPK1 is an intracytoplasmic serine threonine protein kinase that plays an important role in activating the innate immune response to bacteria via TRAF-interacting protein with forkhead-associated domain (TIFA) dependent proinflammatory NF-κB signaling[1]. |
Name | ALPK1-IN-1 |
CAS | 2765457-72-3 |
Formula | C25H32N6O2S |
Molar Mass | 480.63 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Danyang Liu, et al. Alpha protein kinase 1 inhibitors and methods of use. WO2022063152A1. |